Respuesta :

time = distance/speed

The distance between the walkers increases at the rate of (8 mph) -(2 mph) = 6 mph. That distance will be 4.5 mi after ...
  (4.5 mi)/(6 mi/h) = 4.5/6 h = 3/4 h

In 3/4 hour they will be 4.5 miles apart.