PI 3-kinase:_________
A) is counteracted by PTEN phosphatase.
B) is a membrane-associated tyrosine kinase.
C) activates PDK1 by phosphorylating a serine residue on the protein.
D) is only known to be activated by receptor tyrosine kinases.
E) inhibits Akt.

Phosphoinositide 3-kinases or PI-3 kinse, are enzymes involved in essential cellular functions such as the growth of the cell, proliferation, motility, differentiation, survival and intracellular movement, which in turn are plays role in cancer.

PI3-kinase with oncogene PIK3CA and tumor suppressor PTEN, is implicated in the insensitivity of cancer tumors.

Thus, the correct answer is option A)

PI 3-kinase:_________ A) is counteracted by PTEN phosphatase. B) is a membrane-associated tyrosine kinase. C) activates PDK1 by phosphorylating a serine residue on the protein. D) is only known to be activated by receptor tyrosine kinases. E) inhibits Akt.

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PI 3-kinase:_________
A) is counteracted by PTEN phosphatase.
B) is a membrane-associated tyrosine kinase.
C) activates PDK1 by phosphorylating a serine residue on the protein.
D) is only known to be activated by receptor tyrosine kinases.
E) inhibits Akt.