The effects of general anesthesia are mediated by which receptors?
A) Both GABA and NMDA receptors in the CNS
B) Both GABA and NMDA receptors in the PNS
C) Mainly GABA receptors in the CNS
D) Mainly NMDA receptors in the CNS

Respuesta :

Answer:

(A). Both GABA and NMDA receptors in the CNS

Explanation:

General anesthesia or general anesthetics can be defined as substances that triggers a loss of consciousness in individuals. These medications show their effect by activating inhibitory CNS and by inactivation of excitatory receptors of CNS.

They target both GABA (gamma-aminobutyric acid) and NMDA  (N-methyl-D-aspartate) receptors of CNS. General anesthetics agonist effect with GABA receptors and antagonist effect with NMDA receptors, and induces state of unconsciousness.

Thus, the correct answer is option (A).